Our R&D portfolio primarily reflects our scientific, technical and clinical competencies in vector-borne infectious diseases and in both bacterial and viral vaccines.

Vaccine Candidates

We want to make a difference in people’s lives by applying our innovative and pioneering science to address potential vaccine preventable diseases. Our pipeline includes vaccines for infectious diseases with major unmet needs in clinical development, where no vaccines are currently available.

Phase 1
Phase 2
Phase 3
Market Registration
Phase 1
Phase 2
Phase 3
Market Registration

Chikungunya – VLA1553

Chikungunya is a mosquito-borne viral infection spreading in the Americas and Europe caused by the chikungunya virus (CHIKV), a Togaviridae virus transmitted by Aedes mosquitoes. VLA1553 is a live-attenuated, single dose investigational vaccine candidate targeting the chikungunya virus.

View More
Phase 1
Phase 2
Phase 3
Market Registration

Lyme Disease – VLA15

Lyme disease is the most common vector-borne illness in the Northern Hemisphere. Valneva's candidate is the only vaccine in clinical development worldwide. Valneva´s vaccine candidate VLA15, under Fast Track Designation by the FDA, is a multivalent vaccine that targets the outer surface protein A (OspA) of Borrelia.

View More
Phase 1
Phase 2
Phase 3
Market Registration

Shigella – S4V

Shigellosis, caused by Shigella bacteria, is the second leading cause of fatal diarrheal disease worldwide. S4V is the world’s most clinically advanced tetravalent Shigella vaccine candidate.

View More
Phase 1
Phase 2
Phase 3
Market Registration

Zika – VLA1601

A mosquito-borne disease associated with birth defects. Since 1952, Zika outbreaks have been reported in tropical Africa, Southeast Asia, the Pacific Islands, and, in 2015, in the Americas. Valneva’s vaccine candidate, VLA1601, is a highly purified inactivated vaccine candidate against the Zika virus, developed using the same manufacturing platform as Valneva’s Japanese encephalitis vaccine.

View More